Tuesday, May 23, 2023

Can all types of vaccines be given on the same date?

Administration of different vaccines at the same visit both live and inactivated vaccines does not result in decreased antibody responses or increased rates of adverse reaction. Simultaneous administration of all vaccines for which a child is eligible is very important in childhood vaccination programs because it increases the probability that a child will be fully immunized at the appropriate age.



For some vaccines, administration should not be done at different time intervals. The live parenteral (injected) vaccines (MMR, MMRV, varicella, zoster, and yellow fever) and live intranasal influenza vaccine (LAIV should be separated by at least 4 weeks. This interval is intended to reduce or eliminate interference from the vaccine. The yellow fever vaccine Should be administered less than 4 weeks after the single-antigen measles vaccine. A 1999 study demonstrated that the yellow fever vaccine is not affected by the measles vaccine given 1–27 days earlier. Live vaccines administered by the oral route (oral polio vaccine [OPV] oral typhoid, and rotavirus) are not believed to interfere with each other if not given simultaneously. These vaccines may be given at any time before or after each other. The Rotavirus vaccine is not approved for children older than 32 weeks, and oral typhoid is not approved for children younger than 6 years of age.

Parenteral live vaccines (MMR, MMRV, varicella, zoster, and yellow fever) and LAIV are not believed to have an effect on live vaccines given by the oral route (OPV, oral typhoid, and rotavirus). Live oral vaccines may be given at any time before or after live parenteral vaccines or LAIV. All other combinations of two inactivated vaccines, or live and inactivated vaccines, may be given at any time before or after each other.

 

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